Case of Cretinism

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Clinical Remarks on a Case of Sporadic Cretinism

patient, who was kindly sent to me by Dr David Menzies, is suffering from sporadic cretinism?in other words, from the infantile form of myxcedema. She was admitted to the Edinburgh Eoyal Infirmary on March 30th, 1893. At that time, though she did not look more than 2 or 2| years of age, her actual age was 16 years and 4 months. She measured only 29? inches in length, and weighed only 2 st. 5| l...

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Cretinism revisited.

Endemic cretinism includes two syndromes: a more common neurological disorder with brain damage, deaf mutism, squint and spastic paresis of the legs and a less common syndrome of severe hypothyroidism, growth retardation and less severe mental defect. Both conditions are due to dietary iodine deficiency and can be prevented by correction of iodine deficiency before pregnancy. Endemic cretinism ...

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Experimental Cretinism

Findly (1908) and Mellanby (1919) clearly demonstrated that rickets occurred in young animals fed on a diet containing an insufficient amount of certain substances now known as the “antirachitic vitamine.” As a result of this, the British Medical Research Committee announced that rickets is a deficiency disease due to a lack in the diet of an anti-rachitic factor. For literature up to 1923, cov...

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Non-endemic goitrous cretinism.

Enlargement of the thyroid gland is an unusual finding in cretins outside endemic goitrous areas. Wilkins, Clayton and Bertirong (1954), reviewing published cases of non-endemic goitrous cretinism, collected reports of 32 cases and described a further four cases of their own. Other cases have been reported by Rienhoff (1940) and Smallpeice (1949). The hypothyroidism in these cases is of variabl...

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In summarizing the findings of this paper it may be said that degenerative changes have been noted in practically every parenchymatous organ. Among these the most striking has been that of serous imbibition by the most active cells of these organs. In regard to the changes in the glands of internal secretion, the findings corroborate the statements of Cushing in regard to hypophysectomy, that r...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1911

ISSN: 0035-9157

DOI: 10.1177/003591571100401477